Immunobioengineering for Cancer Immunotherapy
Engieered Biomaterials for the Control of Immunity
Biomaterials-based molecular imaging contrast agents
Journal Article
(2022)
Nanoparticle-based delivery strategies of multifaceted immunomodulatory RNA for cancer immunotherapy.
JOURNAL OF CONTROLLED RELEASE.
343,
(2021)
The potential adjuvanticity of cavant®soe for foot-and-mouth disease vaccine.
VACCINES.
9,
10
(2021)
Therapeutic efficacy of cancer vaccine adjuvanted with nanoemulsion loaded with TLR7/8 agonist in lung cancer model.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE.
37,
(2021)
Self-assembled hyaluronic acid nanoparticles for osteoarthritis treatment.
BIOMATERIALS.
275,
(2021)
Molecular and Macroscopic Therapeutic Systems forCytokine-Based Cancer Immunotherapy.
Advanced therapeutics.
2100026
(2020)
Chemical Strategies to Enhance the Therapeutic Efficacy of Toll-like Receptor Agonist Based Cancer Immunotherapy.
ACCOUNTS OF CHEMICAL RESEARCH.
53,
10
(2020)
A three-dimensional hyaluronic acid-based niche enhances the therapeutic efficacy of human natural killer cell-based cancer immunotherapy.
BIOMATERIALS.
247,
(2019)
Improved Sensitivity of Intramolecular Strand Displacement Based on Localization of Probes.
ANALYTICAL CHEMISTRY.
91,
23
(2019)
Lyophilizable and Multifaceted Toll-like Receptor 7/8 Agonist-Loaded Nanoemulsion for the Reprogramming of Tumor Microenvironments and Enhanced Cancer Immunotherapy.
ACS NANO.
13,
11
(2019)
A Designer Scaffold with Immune Nanoconverters for Reverting Immunosuppression and Enhancing Immune Checkpoint Blockade Therapy.
ADVANCED MATERIALS.
31,
42
(2019)
Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence.
NATURE COMMUNICATIONS.
10,
(2019)
Topological Transformation-Based Nanobarcoding for Detection and Enumeration of MicroRNAs and Single Nucleotide Polymorphism.
Advanced Biosystems.
3,
7
(2019)
Protein Nanoparticle Fabrication for Optimized Reticuloendothelial System Evasion and Tumor Accumulation.
LANGMUIR.
35,
11
(2019)
Nanoengineered Immune Niches for Reprogramming the Immunosuppressive Tumor Microenvironment and Enhancing Cancer Immunotherapy.
ADVANCED MATERIALS.
31,
34
(2018)
Targeted cellular delivery of robust enzyme nanoparticles for the treatment of drug-induced hepatotoxicity and liver injury.
ACTA BIOMATERIALIA.
81,
(2018)
Degradation-Regulatable Architectured Implantable Macroporous Scaffold for the Spatiotemporal Modulation of Immunosuppressive Microenvironment and Enhanced Combination Cancer Immunotherapy.
ADVANCED FUNCTIONAL MATERIALS.
28,
47
(2018)
Enhanced Cancer Vaccination by In Situ Nanomicelle-Generating Dissolving Microneedles.
ACS NANO.
12,
10
(2018)
Implantable Synthetic Immune Niche for Spatiotemporal Modulation of Tumor-Derived Immunosuppression and Systemic Antitumor Immunity: Postoperative Immunotherapy.
ADVANCED MATERIALS.
30,
18
(2017)
Fluorescence-coded DNA Nanostructure Probe System to Enable Discrimination of Tumor Heterogeneity via a Screening of Dual Intracellular microRNA Signatures in situ.
SCIENTIFIC REPORTS.
7,
(2017)
Aminated nanomicelles as a designer vaccine adjuvant to trigger inflammasomes and multiple arms of the innate immune response in lymph nodes.
INTERNATIONAL JOURNAL OF NANOMEDICINE.
12,
n
Publications
(2021)
Design of Nanostructure Materials to Modulate Immunosuppressive Tumour Microenvironments and Enhance Cancer Immunotherapy.
Springer Nature.
Lead author
Patent/Intellectual Property
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KOREA, REPUBLIC OF
암 백신 조성물 및 이의 제조 방법.
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KOREA, REPUBLIC OF
생체친화성 음이온 고분자 기반 약물 전달용 조성물 및 이의 제조 방법.
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KOREA, REPUBLIC OF
면역보조제 및 이를 포함하는 백신 조성물.
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KOREA, REPUBLIC OF
면역자극 조성물, 이의 제조 방법, 및 이를 포함하는 면역요법 조성물.
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KOREA, REPUBLIC OF
아주번트 조성물, 이의 제조 방법, 및 이를 포함하는 백신 조성물.
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KOREA, REPUBLIC OF
아주번트 조성물, 이의 제조방법, 및 이를 포함하는 백신 조성물.
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KOREA, REPUBLIC OF
온도감응형 이온성 복합체, 이의 제조 방법, 및 이를 포함하는 생분해성 조성물.
10-2014-0107045.
20151116.
KOREA, REPUBLIC OF
중-대동물 수술가이드용 근적외선 형광 영상장비 및 이를 이용한 이미지화 및 수술가이드 방법.
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KOREA, REPUBLIC OF
활성물질을 담지할 수 있는 표면 딤플구조를 갖는 미립자 및 그 제조방법.
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20141216.
KOREA, REPUBLIC OF
음이온성 고분자와 양이온성 고분자 이온복합체 기반 고감도 자기공명영상 나노조영제 및 이의 제조방법(Sensitive MRI Contrast Nano Agents Based Ionic Complex Containing Anionic and Cationic Polymer and Preparing Method Thereof).
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KOREA, REPUBLIC OF
항체와 나노입자를 세포 내로 동시에 전달할 수 있는다기능성 단백질(Multifunctional Protein Simultaneous Delivering Antibodies and Nanoparticles).
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Conference Paper
(2021)
Modulation of Tumor Microenvironment by a Designer Scaffold with Immune Checkpoint Blockade Enhance Cancer Immunotherapy.
2021년 고분자학회 춘계학술대회.
KOREA, REPUBLIC OF
(2021)
Engineered Macrophage via Click Chemistry Enhances Tumor Targeting and Remodels Immunosuprressive Tumor Microenvironment.
2021년 한국고분자학회 춘계학술대회.
KOREA, REPUBLIC OF
(2020)
Synthetic Immune Niches for Cancer Immunotherapy.
Internationa annual meeting of Korean Tissue Engineering and Regenerative Medicine Society.
KOREA, REPUBLIC OF
(2020)
Reprogramming of immunosuppressive tumor microenvironments by multifunctional nanoemulsion and enhance immune checkpoint blockade therapy.
AACR2020.
UNITED STATES
(2019)
Synthetic Immune Niches for the Modulation of Immunosuppressive Tumor Microenvironments and Enhancing Cancer Immunotherapy.
종양이형성 및 네트워크 제어 연구센터 2019 연례 심포지엄.
KOREA, REPUBLIC OF
(2019)
Synthetic Immune Niches for the Modulation of Tumor Immunosuppressive Microenvironments.
2019 KSMI-KSNM Integration Event Symposium on Molecular Imaging and Nanomedicine.
KOREA, REPUBLIC OF
(2019)
Toll-Like receptor 7/8 agonist-loaded Nanoemulsion Vaccine Adjuvant for the Enhanced Cancer Immunotherapy.
2019 Modern Vaccines Adjuvants & Delivery systems.
SWITZERLAND
(2019)
Nanoengineered platforms to modulate tumor immune microenvironments.
2019 UKC.
UNITED STATES
(2018)
Beyond Adjuvants: Vaccines for Cancer Immunotherapy and Infectious Disease.
International Society for VACCINES 2018 congress.
UNITED STATES
(2018)
Degradation-regulatable architectured implantable macroporous scaffold for the spatiotemporal modulation of immunosuppressive microenvironment and enhanced combination cancer immunotherapy.
Fourth International Cancer lmmunotherapy Conference..
UNITED STATES
(2018)
Implantable Synthetic Immune Hydrogel for Spatiotemporal Modulation of Tumor-derived Immunosuppression and Systemic Antitumor Immunity.
Fourth International Cancer lmmunotherapy Conference.
UNITED STATES
(2018)
Aminated Nanomicelles as Vaccine Adjuvants Induce Inflammasomes and The Innate Immune Response in Lymph nodes.
2018년 대한면역학회 춘계학술대회.
KOREA, REPUBLIC OF
(2018)
Implantable Synthetic Immune Hydrogel for Spatiotemporal Modulation of Tumor-derived Immunosuppression and Systemic Antitumor Immunity.
2018년 대한면역학회 춘계학술대회.
KOREA, REPUBLIC OF
(2018)
Synthetic vaccine nanoparticles target to lymph node triggering enhanced innate and adaptive antitumor immunity.
Keystone symposia Cancer Immunotherapy:Combinations.
CANADA
(2017)
Expeditious detection of hypoxic tumor microenviroments by fluorophore loaded enzyme-responsive nanoparticles.
THIRD CRI-CIMT-EATI-AACR INTERNATIONAL Cancer Immunotherapy Conference.
GERMANY
(2017)
Enhancement of innate and adaptive antitumor immunity by lymph node targeting with synthetic nanoparticle vaccine.
THIRD CRI-CIMT-EATI-AACR INTERNATIONAL Cancer Immunotherapy Conference.
GERMANY
(2017)
Cancer Immunotherapy based on Engineered Nanomaterials.
제53회 한국진공학회 하계정기학술대회 (한국진공학회보).
KOREA, REPUBLIC OF
(2017)
Immune Complexes Mimicking Synthetic Vaccine Nanoparticles for generating Dendritic Cells
with Enhanced Cancer Immunotherapy.
5th International Conference Cancer Immunotherapy & Immunomonitoring (CITIM).
CZECH REPUBLIC
(2017)
Nanoliposomes Reconstituted from Tumor Cell Membranes and Lipid-based Adjuvants for image
guided Cancer Immunotherapy.
5th International Conference Cancer Immunotherapy & Immunomonitoring (CITIM).
CZECH REPUBLIC
(2017)
Engineered Nanomaterials Reshaping Immune Response for Antitumor and Antiviral Immunity.
2017 한국생물공학회 춘계학술발표대회 및 국제심포지엄.
KOREA, REPUBLIC OF