Immunobioengineering for Cancer Immunotherapy
Engieered Biomaterials for the Control of Immunity
Biomaterials-based molecular imaging contrast agents
Journal Articles
(2023)
Nanoengineered Macrophages Armed with TLR7/8 Agonist Enhance Remodeling of Immunosuppressive Tumor Microenvironment.
SMALL.
2307694,
-
(2023)
Molecular Masking of Synthetic Immunomodulator Evokes Antitumor Immunity With Reduced Immune Tolerance and Systemic Toxicity by Temporal Activity Recovery and Sustained Stimulation.
ADVANCED MATERIALS.
(2023)
ProLonged Liposomal Delivery of TLR7/8 Agonist for Enhanced Cancer Vaccine.
VACCINES.
11,
9
(2023)
Kinetics reshape antitumor immunity: Timing, duration, and combination are of importance for successful cancer immunotherapy.
CLINICAL AND TRANSLATIONAL MEDICINE.
13,
9
(2023)
Discovery of highly immunogenic spleen-resident FCGR3+CD103+ cDC1s differentiated by IL-33-primed ST2+ basophils.
CELLULAR & MOLECULAR IMMUNOLOGY.
20,
7
(2023)
Protective Efficacy and Immunogenicity of Rv0351/Rv3628 Subunit Vaccine Formulated in Different Adjuvants Against Mycobacterium tuberculosis Infection.
IMMUNE NETWORK.
23,
2
(2023)
A nanoadjuvant that dynamically coordinates innate immune stimuli activation enhances cancer immunotherapy and reduces immune cell exhaustion.
NATURE NANOTECHNOLOGY.
18,
1
(2022)
Nanoengineered drug delivery in cancer immunotherapy for overcoming immunosuppressive tumor microenvironment.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH.
13,
7
(2022)
Fabrication of Drug-Loaded Calcium Phosphate Nanoparticles: An Investigation of Microbial Toxicity.
JOURNAL OF CLUSTER SCIENCE.
33,
5
(2022)
In Situ-Forming Collagen/poly-gamma-glutamic Acid Hydrogel System with Mesenchymal Stem Cells and Bone Morphogenetic Protein-2 for Bone Tissue Regeneration in a Mouse Calvarial Bone Defect Model.
TISSUE ENGINEERING AND REGENERATIVE MEDICINE.
19,
5
(2022)
Nanoparticle-based delivery strategies of multifaceted immunomodulatory RNA for cancer immunotherapy.
JOURNAL OF CONTROLLED RELEASE.
343,
-
(2021)
The potential adjuvanticity of cavant®soe for foot-and-mouth disease vaccine.
VACCINES.
9,
10
(2021)
Therapeutic efficacy of cancer vaccine adjuvanted with nanoemulsion loaded with TLR7/8 agonist in lung cancer model.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE.
37,
(2021)
Self-assembled hyaluronic acid nanoparticles for osteoarthritis treatment.
BIOMATERIALS.
275,
(2021)
Molecular and Macroscopic Therapeutic Systems forCytokine-Based Cancer Immunotherapy.
Advanced therapeutics.
2100026
(2020)
Chemical Strategies to Enhance the Therapeutic Efficacy of Toll-like Receptor Agonist Based Cancer Immunotherapy.
ACCOUNTS OF CHEMICAL RESEARCH.
53,
10
(2020)
A three-dimensional hyaluronic acid-based niche enhances the therapeutic efficacy of human natural killer cell-based cancer immunotherapy.
BIOMATERIALS.
247,
(2019)
Improved Sensitivity of Intramolecular Strand Displacement Based on Localization of Probes.
ANALYTICAL CHEMISTRY.
91,
23
(2019)
Lyophilizable and Multifaceted Toll-like Receptor 7/8 Agonist-Loaded Nanoemulsion for the Reprogramming of Tumor Microenvironments and Enhanced Cancer Immunotherapy.
ACS NANO.
13,
11
Publications
(2021)
Design of Nanostructure Materials to Modulate Immunosuppressive Tumour Microenvironments and Enhance Cancer Immunotherapy.
Springer Nature.
Lead author
Patent/Intellectual Property
CRYOGEL SCAFFOLD CAPABLE OF CONTROLLING DEGREE OF DEGRADATION
AND SOFT BIO-INTEGRATED DEVICE IN WHICH DRUG MODULATING
IMMUNOSUPPRESSIVE ACTION IN SOLID MICROENVIRONMENT IS LOADED IN
SAME SCAFFOLD.
16/954,324.
20230112.
UNITED STATES
THERMOSENSITIVE IONIC COMPOSITE, PREPARING METHOD THEREOF, AND
BIODEGRADABLE COMPOSITION CONTAINING THE SAME.
14/828,876.
20180828.
UNITED STATES
재구성 인공 암세포, 이의 제조방법, 및 이를 포함하는 항암조성물.
10-2017-0000357.
20180523.
KOREA, REPUBLIC OF
폴리감마글루탐산 함유 하이드로겔 및 이를 포함하는 의료용 접착제 및 지혈제.
10-2016-0026130.
20180427.
KOREA, REPUBLIC OF
약물 전달용 조성물 및 이의 제조방법.
10-2016-0116955.
20171201.
KOREA, REPUBLIC OF
약물전달 조성물, 및 감염질환 진단 및 치료용 조성물.
10-2015-0050833.
20161007.
KOREA, REPUBLIC OF
암 백신 조성물 및 이의 제조 방법.
10-2015-0050843.
20160804.
KOREA, REPUBLIC OF
생체친화성 음이온 고분자 기반 약물 전달용 조성물 및 이의 제조 방법.
10-2014-0112655.
20160802.
KOREA, REPUBLIC OF
아주번트 조성물 및 백신 조성물의 제조 방법.
10-2015-0073826.
20160215.
KOREA, REPUBLIC OF
면역보조제 및 이를 포함하는 백신 조성물.
10-2014-0195268.
20160112.
KOREA, REPUBLIC OF
면역자극 조성물, 이의 제조 방법, 및 이를 포함하는 면역요법 조성물.
10-2014-0195270.
20160112.
KOREA, REPUBLIC OF
아주번트 조성물, 이의 제조 방법, 및 이를 포함하는 백신 조성물.
10-2014-0193994.
20160112.
KOREA, REPUBLIC OF
아주번트 조성물, 이의 제조방법, 및 이를 포함하는 백신 조성물.
10-2014-0195269.
20151210.
KOREA, REPUBLIC OF
온도감응형 이온성 복합체, 이의 제조 방법, 및 이를 포함하는 생분해성 조성물.
10-2014-0107045.
20151116.
KOREA, REPUBLIC OF
중-대동물 수술가이드용 근적외선 형광 영상장비 및 이를 이용한 이미지화 및 수술가이드 방법.
1020130015119.
20150429.
KOREA, REPUBLIC OF
활성물질을 담지할 수 있는 표면 딤플구조를 갖는 미립자 및 그 제조방법.
1020130046966.
20141216.
KOREA, REPUBLIC OF
음이온성 고분자와 양이온성 고분자 이온복합체 기반 고감도 자기공명영상 나노조영제 및 이의 제조방법(Sensitive MRI Contrast Nano Agents Based Ionic Complex Containing Anionic and Cationic Polymer and Preparing Method Thereof).
10-2011-0031665.
20140515.
KOREA, REPUBLIC OF
항체와 나노입자를 세포 내로 동시에 전달할 수 있는다기능성 단백질(Multifunctional Protein Simultaneous Delivering Antibodies and Nanoparticles).
10-2007-0074759.
20091102.
KOREA, REPUBLIC OF
Conference Paper
(2023)
Materials for kinetic immune modulation reshape immunity.
2023 International Conference of the Korean Society of Pharmaceutical Science and Technology.
KOREA, REPUBLIC OF
(2023)
Immune Designer for Dynamic Tailoring of Innate Immunity.
2023년 한국고분자학회 추계 정기총회 및 학술대회.
KOREA, REPUBLIC OF
(2023)
Dynamic Coordination of Innate Immunity for Enhanced Cancer Immunotherapy and Reduction of Immune Cell Exhaustion by Using Kinetically Activating Nanoadjuvant.
Seventh CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference.
ITALY
(2023)
Dynamic Coordination of Innate Immunity for Enhanced Cancer Immunotherapy and Reduction of Immune Cell Exhaustion by Using Kinetically Activating Nanoadjuvant.
KAI International Meeting 2023.
KOREA, REPUBLIC OF
(2023)
Time-controled DC activation for enhanced cancer immunotherapy.
KAI International Meeting 2023.
KOREA, REPUBLIC OF
(2023)
Engineered Macrophages Anchored with Toll-like Receptor 7/8 Agonist by Click Chemistry Enhance Antitumor Immunity.
KAI International Meeting 2023.
KOREA, REPUBLIC OF
(2023)
Reprogramming TME with immunostimulator and blockade of SIRPα-CD47 axis enhances antitumor innate immunity.
KAI International Meeting 2023.
KOREA, REPUBLIC OF
(2023)
Designer Vaccine Adjuvant/immunomodulators for Injectious Disease.
대한바이러스 학회 연구회 연합 정기 학술대회.
KOREA, REPUBLIC OF
(2022)
Controlling Chemoimmunotherapy-induced Immunosuppression by Assemblable
Immune Modulating Nanosuspension Combined with Supra-adjuvant.
2022 한국생물공학회 추계학술발표대회 및 국제심포지엄.
KOREA, REPUBLIC OF
(2022)
Novel vaccine adjuvants empowered by coded signal integration.
바이러스연구포럼.
KOREA, REPUBLIC OF
(2021)
Modulation of Tumor Microenvironment by a Designer Scaffold with Immune Checkpoint Blockade Enhance Cancer Immunotherapy.
2021년 고분자학회 춘계학술대회.
KOREA, REPUBLIC OF
(2021)
Engineered Macrophage via Click Chemistry Enhances Tumor Targeting and Remodels Immunosuprressive Tumor Microenvironment.
2021년 한국고분자학회 춘계학술대회.
KOREA, REPUBLIC OF
(2020)
Synthetic Immune Niches for Cancer Immunotherapy.
Internationa annual meeting of Korean Tissue Engineering and Regenerative Medicine Society.
KOREA, REPUBLIC OF
(2020)
Reprogramming of immunosuppressive tumor microenvironments by multifunctional nanoemulsion and enhance immune checkpoint blockade therapy.
AACR2020.
UNITED STATES
(2019)
Synthetic Immune Niches for the Modulation of Immunosuppressive Tumor Microenvironments and Enhancing Cancer Immunotherapy.
종양이형성 및 네트워크 제어 연구센터 2019 연례 심포지엄.
KOREA, REPUBLIC OF
(2019)
Synthetic Immune Niches for the Modulation of Tumor Immunosuppressive Microenvironments.
2019 KSMI-KSNM Integration Event Symposium on Molecular Imaging and Nanomedicine.
KOREA, REPUBLIC OF
(2019)
Toll-Like receptor 7/8 agonist-loaded Nanoemulsion Vaccine Adjuvant for the Enhanced Cancer Immunotherapy.
2019 Modern Vaccines Adjuvants & Delivery systems.
SWITZERLAND
(2019)
Nanoengineered platforms to modulate tumor immune microenvironments.
2019 UKC.
UNITED STATES
(2018)
Beyond Adjuvants: Vaccines for Cancer Immunotherapy and Infectious Disease.
International Society for VACCINES 2018 congress.
UNITED STATES
(2018)
Degradation-regulatable architectured implantable macroporous scaffold for the spatiotemporal modulation of immunosuppressive microenvironment and enhanced combination cancer immunotherapy.
Fourth International Cancer lmmunotherapy Conference..
UNITED STATES
