Research Interest
Part 1. Protein-Based Materials
⁃ Development of protein-based gels with non-biodegradability, electrical conductivity, and biocompatibility
⁃ Design of protein environments that mimic the extracellular matrix (ECM)
⁃ Control of gel properties for biosensing and drug delivery
Part 2. Supramolecular Self-Assembly
⁃ Modularization of supramolecular structures through coiled-coil–based self-assembly
⁃ Self-assembly of protein-induced fullerene crystals
Part 3. Regulation of Cell Behavior Using Proteins
⁃ Construction of a multifunctional Mussel Adhesive Protein (MAP) library
⁃ Regulation of cell activity and morphology using functional proteins
Education
• 2011–2013 Postdoctoral Researcher, Massachusetts Institute of Technology (MIT), USA
• 2005–2011 Ph.D. in Biochemistry, University of Pennsylvania (UPenn), USA
• 2001–2003 M.S. in Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Korea
Experience
• 2019–Present Associate Professor, Department of Nano Engineering & Institute of Nanoscience and Technology (SAINT), Sungkyunkwan University
• 2019–Present Co-founder, CTO & Vice President, IMNEURON Co., Ltd.
• 2015–2018 Assistant Professor, Department of Biomedical Engineering, Sungkyunkwan University
• 2013–2018 Assistant Professor, Institute of Nanoscience and Technology (SAINT) & Department of Chemistry, Sungkyunkwan University
• 2004–2005 Research Engineer, LG Chem Research & Development Center, Korea
Journal Articles
• (2025) Biosupercapacitors for Human-Powered Electronics. ADVANCED FUNCTIONAL MATERIALS. e10680
• (2025) Intersection-Free Fractal-Like Structuring of Recombinant Adhesive Proteins for Surface Functionalization. NANO LETTERS. 25, 33
• (2025) Artificial Intelligence-Driven Nanoarchitectonics for Smart Targeted Drug Delivery. ADVANCED MATERIALS. n/a, n/a
• (2025) Strategic Lithium-Ion Battery Recycling for Global Resource Challenges. Carbon Neutralization. n/a, n/a
• (2025) Nocardioides eburneus sp. nov., isolated from commercial soil. INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY. 75, 4
• (2025) Design of a light and Ca2+ switchable organic–peptide hybrid. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 122, 5
• (2024) Structure-Guided Engineering of Thermodynamically Enhanced SaCas9 for Improved Gene Suppression. ADVANCED MATERIALS.
• (2024) Peptide-Drug Conjugate with Statistically Designed Transcellular Peptide for Psoriasis-Like Inflammation. ADVANCED HEALTHCARE MATERIALS. 13, 15
• (2023) Mechanistic insights into the anti-restenotic effects of HSP27 and HO1 modulated by reconstituted HDL on neointimal hyperplasia. SCIENTIFIC REPORTS. 13, 1
• (2023) Mussel-Inspired Recombinant Adhesive Protein-Based Functionalization for Consistent and Effective Antimicrobial Treatment in Chronic Inflammatory Skin Diseases. ADVANCED THERAPEUTICS. 7, 4
• (2023) Plasmonic digital PCR for discriminative detection of SARS-CoV-2 variants. BIOSENSORS & BIOELECTRONICS. 246, 1
• (2023) Peptide-nanoparticle conjugates as a theranostic platform. COORDINATION CHEMISTRY REVIEWS. 500, 1
• (2023) Multidisciplinary approaches for enzyme biocatalysis in pharmaceuticals: protein engineering, computational biology, and nanoarchitectonics. EES Catalysis. 2, 1
• (2023) Peptide-Assembled Single-Chain Atomic Crystal Enhances Pluripotent Stem Cell Differentiation to Neurons. NANO LETTERS. 23, 15
• (2023) Synthesis Strategies and Nanoarchitectonics for High-Performance Transition Metal Dichalcogenide Thin Film Field-effect Transistors. CHEMNANOMAT. 9, 7
• (2023) Wearable and implantable bioelectronics as eco-friendly and patient-friendly integrated nanoarchitectonics for next-generation smart healthcare technology. ECOMAT. 5, 8
• (2023) Citrous Lime—A Functional Reductive Booster for Oil-Mediated Green Synthesis of Bioactive Silver Nanospheres for Healthcare Clothing Applications and Their Eco-Mapping with SDGs. MOLECULES. 28, 6
• (2022) Effect of Secondary Structures on the Adsorption of Peptides onto Hydrophobic Solid Surfaces Revealed by SALDI-TOF and MD Simulations. ACS OMEGA. 7, 48
• (2022) Effect of Secondary Structure on Adsorption of Peptides onto Hydrophobic Solid Surface Revealed by SALDI-TOF and MD Simulations. ACS OMEGA. 7, 48
• (2022) Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling. NATURE CELL BIOLOGY. 24, 12
Patent/Intellectual Property
• Nucleic acid molecules with improved stability and uses thereof. 10-2020-0067831. 2021-05-26. Republic of Korea
• Novel cell-penetrating peptides and skin-improving compositions comprising the same. 10-2020-0055044. 2021-01-19. Republic of Korea
• Composition for bio-signal measurement and stimulation containing biocompatible conductive protein gel. 10-2017-0116637. 2020-09-07. Republic of Korea
• Nanocomposite and method for manufacturing a dispersion including the nanocomposite. 10-2135-2210000. 2020-07-13. Republic of Korea
• Method for manufacturing a biosensor platform using graphene and proteins, biosensor platform manufactured thereby, and field-effect transistor-type biosensor comprising the same. 10-2015-0154991. 2017-11-10. Republic of Korea
• Coiled-coil protein and use thereof. 10-1798-7470000. 2017-11-09. Republic of Korea
• Biocompatible protein, biocompatible protein gel, and biocompatible conductive protein gel comprising the protein, and method for preparing the same. 14/811,350. 2017-05-16. United States
• Biocompatible protein, biocompatible protein gel and conductive protein gel comprising the same, and method for preparing the same. 10-2015-0016171. 2015-09-01. Republic of Korea
Honors / Awards
• Patent: Biocompatible protein, biocompatible protein gel, and method for preparing a conductive protein gel comprising the same
• Patent: Peptide design for novel antibody-based probe development and method thereof